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The results indicated that the addition of ezetemibe — which blocks the absorption of cholesterol in the intestines and is the key component that has turned vytorin into a multibillion-dollar blockbuster — produces no additional benefit.

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Information about Vytorin.

No dosage adjustment is necessary in geriatric patientssee CLINICAL PHARMACOLOGY

4Product InformationVytorinezetimibe-simvastatinMerckCompany IncWest PointPA.

Read the Patient Information Leaflet if available from your pharmacist before you start taking this product and each time you get a refillIf you have any questionsask your doctor or pharmacist.

VYTORIN is indicated for the reduction of elevated total-C and LDL-C in patients with homozygous familial hypercholesterolemiaas an adjunct to other lipid-lowering treatmentse.gLDL apheresisor if such treatments are unavailable.

This medicine should not be given to a girl who has not yet had menstrual periods.

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in a multicenter, double-blind, 6-week study, 1902 patients with primary hyperlipidemia, who had not met their ncep atp iii target ldl-c goal, were randomized to one of eight treatment groups vytorin 10 10, 10 20, 10 40, or 10 80 or atorvastatin 10 mg, 20 mg, 40 mg, or 80 mg .

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