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You should not stop using nimodipine suddenlyStopping suddenly may make your condition worse.
Before taking nimodipinetell your doctor if you have liver diseaselow blood pressurehigh blood pressurehypertensionfor which you take medicineor a history of heart problems such as a slow heart ratecongestive heart failureor heart attack.
Concomitant administration of oral nimodipine and diazepamdigoxinglibenclamideindometacinranitidine and warfarin did not reveal any potential for mutual interaction.
Nimodipine is a calcium channel blockerThe contractile processes of smooth muscle cells are dependent upon calcium ionswhich enter these cells during depolarization as slow ionic transmembrane currentsNimodipine inhibits calcium ion transfer into these cells and thus inhibits contractions of vascular smooth muscleIn animal experimentsnimodipine had a greater effect on cerebral arteries than on arteries elsewhere in the body perhaps because it is highly lipophilicallowing it to cross the blood-brain barrierconcentrations of nimodipine as high as 12.5 ng/mL have been detected in the cerebrospinal fluid of nimodipine-treated subarachnoid hemorrhageSAHpatients.
Mild dizzinessflushingrednesswarmthor tingling feelingheadachenauseaconstipationor sweating.
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