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Iris color change may not be noticeable for several months to yearsTypicallythe brown pigmentation around the pupil spreads concentrically towards the periphery of the iris and the entire iris or parts of the iris become more brownishNeither nevi nor freckles of the iris appear to be affected by treatmentWhile treatment with XALATAN can be continued in patients who develop noticeably increased iris pigmentationthese patients should be examined regularlysee PATIENT INFORMATION

The usual dose is one drop into the affected eye or eyes once daily in the eveningThe hands should be washed before each use of latanoprost or any eye medicationContact lenses should be removedThe head is tilted back and the lower eyelid is pulled down with the index finger to form a pouchIt is important not to touch the tip of the dropper to the eye or the eyelid so that bacteria are not introduced into the bottleThe bottle is squeezed slightly to allow the prescribed number of drops into the pouchThe eye is closed gently for 2 to 3 minutes without blinking.

It is not known whether Xalatan eye drops will harm an unborn babyTell your doctor if you are pregnant or plan to become pregnant.

Discoloration of the iris begins slowlyIt is caused by an increase in the amount of brown pigment in the iris and may be permanentOther side effects which have been reported less frequently include:

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effectsMany people using this medication do not have serious side effects.

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