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Prednisone is very effective but has significant side effects.

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Generic drugs usually cost less than the brand-name versionIn some casesthey may not be available in all strengths or forms as the brand-name drug.

DisclaimerOur goal is to provide you with the most relevant and current informationHoweverbecause drugs affect each person differentlywe cannot guarantee that this information includes all possible side effectsThis information is not a substitute for medical adviceAlways discuss possible side effects with a healthcare provider who knows your medical history.

Changes in the shape or location of body fatespecially in your armslegsfaceneckbreastsand waist

The rationale for this treatment schedule is based on two major premisesathe anti-inflammatory or therapeutic effect of corticoids persists longer than their physical presence and metabolic effects andbadministration of the corticosteroid every other morning allows for re-establishment of more nearly normal hypothalamic-pituitary-adrenalHPAactivity on the off-steroid day.

Taking warfarin with prednisone may reduce the blood-thinning effect of warfarinIf you take these drugs togetheryour doctor may monitor your treatment with warfarin closely.

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ivacaftor is an inhibitor of cyp3a and p-glycoprotein pgp ; prednisone is a substrate of pgp and it s active metabolite, prednisolone, is metabolized by cyp3a.

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