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The effect of concomitant multiple dosing of warfarin and pletal on the pharmacodynamics of both drugs is unknown.

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Patients may respond as early as 2 to 4 weeks after the initiation of therapybut treatment for up to 12 weeks may be needed before a beneficial effect is experiencedIf symptoms are unimproved after 3 monthsdiscontinue Pletal.

Torsade de pointes and QTc prolongation in patients with cardiac disorderse.gcomplete atrioventricular blockheart failureand bradyarrythmiaangina pectoris.

Figure 2 depicts the percent mean improvement in maximal walking distanceat study end for each of the eight studies.

Cilostazol should be initiated by physicians experienced in the management of intermittent claudicationsee also section 4.4

Cilostazol may cause dizziness and patients should be warned to exercise caution before they drive or operate machinery.

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pletal is a prescription medicine used to reduce the symptoms of intermittent claudication and can increase your ability to walk further distances.

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