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MAXZIDEtriamterene and hydrochlorothiazideis a diureticantihypertensive drug productprincipally due to its hydrochlorothiazide componentthe triamterene component of MAXZIDE reduces the excessive potassium loss which may occur with hydrochlorothiazide use.

OtherElevated liver enzymes have been reported in patients receiving MAXZIDE.

The exact mechanism of hydrochlorothiazide’s antihypertensive action is not known although it may relate to the excretion and redistribution of body sodium.

Triamterene may be used alone or with other diureticseither for its added diuretic effect or its potassium-sparing potentialIt also promotes increased diuresis when patients prove resistant or only partially responsive to thiazides or other diuretics because of secondary hyperaldosteronism.

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