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Selective Serotonin Reuptake Inhibitors/Serotonin Norepinephrine Reuptake Inhibitors and Serotonin Syndrome.

The undesirable effects observed with the administration of rizatriptan are dizzinesssomnolenceparaesthesiaheadachehypaesthesiadecreased mental acuitytremorhot flushes/flashespharyngeal discomfortdyspnoeapalpitationtachycardiapaintightness/pressure and/or heavy sensation in the chestneckthroat or jawregional heavinesspain in locations unspecifieddry mouthnauseavomitingdiarrhoeaflushingsweatingand asthenia/fatigue.

Vomiting Nausea Sensitivity to sound or light Pain in the temples Temporary loss of vision Pain behind your ear or eye.

Cases of life-threatening serotonin syndrome have been reported during combined use of selective serotonin reuptake inhibitorsSSRIsor serotonin norepinephrine reuptake inhibitorsSNRIsand triptansThere have been reports describing patients with symptoms compatible with serotonin syndromeincluding altered mental statusautonomic instability and neuromuscular abnormalitiesfollowing the use of SSRIs or serotonin norepinephrine reuptake inhibitorsSNRIsand triptans.

In patients receiving propranololthe 5mg dose of RIZACT Tablets should be usedup to a maximum of three doses in any 24-hour period.

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